Children are less likely to get the coronavirus than adults.
Researchers say children are less likely to get coronary heart disease.
The global war on coronavirus has been underway since March. We eventually learned that the virus is as deadly to adults as it is to adults; And not that dangerous for children.
The researchers found a good reason for this.
The study was published in the Journal of Clinical Research.
How children suffer less
For proper infection, the coronavirus must enter the "epithelial cells" of the lungs. And the "enzyme" or "coreceptor" by which the virus does this is less common in children than in adults and the elderly.
The study says that if the enzyme could be suppressed, adults could be protected from Covid-19 and the disease could be cured.
We still know a lot about the coronavirus. Until now, however, it was known that as soon as a virus enters the lungs by inhalation, its protein "adhesions" or bumps attach themselves to a receptor called ACE-II. These "receptors" are found on the surface of some lung cells.
Next, an enzyme in the cell called TMPRSS cuts and breaks down the crests of this protein. The virus mixes with the cell's "membrane" and at some point enters the cell.
Inside the cell, the virus takes control of the cell's internal genetic control and begins making copies of its own RNA.
The research was conducted by Jennifer Sucre, assistant professor in the department of pediatrics at the Vanderbelt University Medical Center in the United States. He was accompanied by Jonathan Kropsky, assistant professor in the medical department.
They believe that the intensity of Covid-19 is higher in adults and lower in children, due to the TMPRSS enzyme.
With the help of pathologists at Vanderbelt University Medical Center, researchers took lung cell samples from people of all ages.
Information on the development of the lungs with age is obtained through sequencing of "single-celled RNA".
It can be seen that the activity of TMPRSS increases with age.
"The effects of these enzymes are present in both genes and proteins," said Sucre.
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